Smart Money · Holder IQ
63 / 100
Above median holder quality (percentile 79.3 this quarter). Tracked high-scoring holders are adding shares.
AGIO
Agios PharmNASDAQ
Healthcare • Biotechnology
Factor tilt: Small-Cap Blend
$31.76+1.21%
Close Nov 10, 2026
- Market cap
- $1.89B
- 1 month
- +3.0%
- 3 months
- -7.2%
- 1 year
- -21.9%
- 52-week range
- $22.34$45.49
Reading stored signals…
More market facts
- Dividend
- No dividends on record
- Short interest
- 13.0% of float6.5M shares · settled Oct 30, 2026 · -5.4% since Oct 15, 2026 · FINRA
Fundamentals · trailing 12 months to Sep 30, 2026
- Revenue
- $140.84M
- Net income
- -$372.9M
- Free cash flow
- -$335.97M
- Book value
- $979.34M
- Total debt
- $26.53M
- P/E
- —
- Price / sales
- 13.4×
- Price / book
- 1.9×
- FCF yield
- -17.8%
- Net margin
- -264.8%
EODHD (TTM) · as of Nov 10, 2026
End-of-day close from stored market data, not a live quote.
About Agios Pharm
Agios Pharmaceuticals, Inc., a biopharmaceutical company, discovers and develops medicines in the field of cellular metabolism in the United States. Its lead product includes PYRUKYND (mitapivat), an activator of wild-type and mutant pyruvate kinase (PK), enzymes used for the treatment of hemolytic anemias in adults with PK deficiency.
Read more
The company's PYRUKYND product is also used for the treatment of sickle cell disease that is in phase 3 clinical trial; for the treatment of PK deficiency in pediatric patients; and AQVESME for the treatment of adult patients with non-transfusion dependent and transfusion-dependent alpha- or beta-thalassemia. In addition, it developed tebapivat, a PK activator for the treatment of lower-risk myelodysplastic syndrome and sickle cell disease; AG-181, a phenylalanine hydroxylase stabilizer for the treatment of phenylketonuria (PKU); and AG-236, an siRNA in-licensed from Alnylam, targeting the transmembrane serine protease 6 (TMPRSS6) gene for the treatment of polycythemia vera. Agios Pharmaceuticals, Inc. was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.
- Website
- agios.com
- Headquarters
- Cambridge, MA, United States
- Employees
- 539
- Listed
- Jul 24, 2013
- Fiscal year ends
- December
Company profile from EODHD, stored Nov 11, 2026.
Quarterly results
The last 8 fiscal quarters from EODHD’s latest stored vendor-normalized figures. These may include restatements. Year over year compares the same quarter a year earlier.
| Quarter | Revenue | YoY | Gross margin | Op. income | Net income |
|---|---|---|---|---|---|
| Sep 2026filed Nov 5, 2026 | $55.4M | +330.0% | 95.4% | -$77.2M | -$65.0M |
| Jun 2026filed Jul 30, 2026 | $44.7M | +259.3% | 93.3% | -$110.6M | -$100.7M |
| Mar 2026filed Apr 29, 2026 | $20.7M | +137.7% | 87.1% | -$110.0M | -$99.1M |
| Dec 2025filed Feb 12, 2026 | $20.0M | +86.1% | 84.2% | -$121.6M | -$108.0M |
| Sep 2025filed Oct 30, 2025 | $12.9M | +43.7% | 76.3% | -$116.9M | -$103.4M |
| Jun 2025filed Jul 31, 2025 | $12.5M | +44.6% | 76.2% | -$127.1M | -$112.0M |
| Mar 2025filed May 1, 2025 | $8.7M | +6.6% | 72.9% | -$106.6M | -$89.3M |
| Dec 2024filed Feb 13, 2025 | $10.7M | +51.1% | 88.3% | -$125.0M | -$96.5M |
Balance sheet · cash, debt and near-term obligations
What resources sit beside the obligations? These are balances at each fiscal quarter end, not cash earned during the quarter. Amounts are in USD, the reporting currency.
As of
- Reported cash
- $128.5M
- Reported total debt
- $26.5M
- Current assets
- $752.1M
- Current liabilities
- $77.6M
Vendor filing date:
As of
- Reported cash
- $99.6M
- Reported total debt
- $31.2M
- Current assets
- $717.7M
- Current liabilities
- $70.2M
Vendor filing date:
As of
- Reported cash
- $113.6M
- Reported total debt
- $35.7M
- Current assets
- $834.8M
- Current liabilities
- $58.8M
Vendor filing date:
As of
- Reported cash
- $89.1M
- Reported total debt
- $40.2M
- Current assets
- $942.1M
- Current liabilities
- $82.2M
Vendor filing date:
Link an account to see your stake, watchlist and past holdings. Compare cash and debt across dates when reviewing its reliance on financing. Current assets can include receivables and inventory; current liabilities include bills as well as borrowings. They are not all spendable cash or all debt. These figures alone do not establish the ability to repay.
Source: EODHD’s latest stored vendor-normalized balance sheets, matched to the same security and fiscal end as these income periods. They may include restatements and are not an originally-filed or knowledge-time history. No net debt, coverage ratio or replacement balance is calculated. Read the SEC guide to financial statements for the distinction between balances and cash flows.
Company Quality Grade
How steadily did the business compound its per-share book value with dividends over 40 quarters? This historical measure is not a stock-price return or a forecast.
No published 40-quarter grade for this issuer. This is not a zero or a poor-quality verdict.
Link an account to see your stake, watchlist and past holdings. Use this to question the durability of the business behind your investment case, alongside its filings and valuation. A withheld grade is a data or method limit, not a sell signal. For a short position, it does not predict timing, borrowing costs or downside. It does not measure your account’s return.
People-network credibility
The people behind a company influence capital allocation and controls. This published research measures graph connections to people with admitted adjudications (RED), and to repeat value creators or stewards of qualifying compounders and long-term shareholder-return leaders (GREEN). Connections alone do not establish conduct. These measures are separate from insider trading performance and Company Quality Grade.
Reporting owners who filed from after Oct 9, 2025 through Oct 9, 2026: a 12-month window ending at the publication date. This can include former officers and directors; it is not a verified roster of today's employees.
- Reporting owners in the filing window
- 16
- In the published population
- 16
- With a calibrated score
- 0
0 outside the population; 16 population members without a calibrated score. These are issuer-wide counts, not counts of the preview below. Neither state is a favorable or adverse finding.
When calibrated measures are published, RED and GREEN are separately calibrated graph proximities. NetCredibility is GREEN minus RED, on a −1 to 1 scale, not a probability or expected return. Both poles and their published intervals stay visible. A positive net does not erase an admitted finding.
Link an account to see your stake, watchlist and past holdings. Use the cited filings to check who was reporting a role and review the published evidence alongside your investment thesis. A gap calls for checking the underlying record; it does not tell you to increase or reduce a holding.
Showing 8 of 16 reporting owners, ordered by filed role and name, not by score. This preview is not an issuer score or a comparison with other companies.
Jay T. Backstrom
Director — as filed
No calibrated score published
The publication withholds a net score. Its stated reason is available in the source details.
No admitted adjudication is listed for this person in this publication.
Read the 4 filed Jul 10, 2026Person source details
- Reporting-owner CIK
- 0001796398
- Published reason
- calibration abstention: no fitted calibration
- Score identity
- bdfe98e525c3d36b0264eaf9a1b4c80da9dee9ddd14d6ee24085add4d00005cf
- Publication's adjudication label
- none
Rahul D. Ballal
Director — as filed
No calibrated score published
The publication withholds a net score. Its stated reason is available in the source details.
No admitted adjudication is listed for this person in this publication.
Read the 4 filed Jun 23, 2026Person source details
- Reporting-owner CIK
- 0001805097
- Published reason
- calibration abstention: no fitted calibration
- Score identity
- 474bfa481dbd94236a5f245c414342af247902586b789cf87b226fdc3f3fc082
- Publication's adjudication label
- none
James William Burns
Chief Legal Officer — as filed
No calibrated score published
The publication withholds a net score. Its stated reason is available in the source details.
No admitted adjudication is listed for this person in this publication.
Read the 4 filed Jun 23, 2026Person source details
- Reporting-owner CIK
- 0001900772
- Published reason
- calibration abstention: no fitted calibration
- Score identity
- c0c7072d7f7037fbeed3f852aee4f0668523b4345b253cbf4d534aef7c3ab8c3
- Publication's adjudication label
- none
Jeffrey D. Capello
Director — as filed
No calibrated score published
The publication withholds a net score. Its stated reason is available in the source details.
No admitted adjudication is listed for this person in this publication.
Read the 4 filed Jun 23, 2026Person source details
- Reporting-owner CIK
- 0001224108
- Published reason
- calibration abstention: no fitted calibration
- Score identity
- e9c2fb7bbe2405324613a5c500d196b5fb5e140a906f27935fa0d46dffc9ce38
- Publication's adjudication label
- none
Kaye I. Foster-Cheek
Director — as filed
No calibrated score published
The publication withholds a net score. Its stated reason is available in the source details.
No admitted adjudication is listed for this person in this publication.
Read the 4 filed Jun 23, 2026Person source details
- Reporting-owner CIK
- 0001312622
- Published reason
- calibration abstention: no fitted calibration
- Score identity
- 38f682c6a456b3dabee621ac3fabe21b9f2085ee55902fe663a7c1e5a9ef8218
- Publication's adjudication label
- none
Jacqualyn A. Fouse
Director — as filed
No calibrated score published
The publication withholds a net score. Its stated reason is available in the source details.
No admitted adjudication is listed for this person in this publication.
Read the 4 filed Jun 23, 2026Person source details
- Reporting-owner CIK
- 0001405288
- Published reason
- calibration abstention: no fitted calibration
- Score identity
- 4226c66313125ff958c9c87e254bb0c2a4e6d0c7de1586640333921ad8f1d3a1
- Publication's adjudication label
- none
Sarah Gheuens
Chief Medical Officer — as filed
No calibrated score published
The publication withholds a net score. Its stated reason is available in the source details.
No admitted adjudication is listed for this person in this publication.
Read the 4 filed Aug 6, 2026Person source details
- Reporting-owner CIK
- 0001881190
- Published reason
- calibration abstention: no fitted calibration
- Score identity
- e89497c90303ff00530cbd16eb3ba3eeaca98bf13e1e66b575534e979847c54b
- Publication's adjudication label
- none
Brian Goff
Chief Executive Officer · Director — as filed
No calibrated score published
The publication withholds a net score. Its stated reason is available in the source details.
No admitted adjudication is listed for this person in this publication.
Read the 4 filed Jun 23, 2026Person source details
- Reporting-owner CIK
- 0001546216
- Published reason
- calibration abstention: no fitted calibration
- Score identity
- 01a291b694d4d593878217af6f86448b7fcb1ebccb42f003c79e3a5975c4ad44
- Publication's adjudication label
- none
Admitted findings are published guilty pleas, convictions and litigated SEC judgments or orders. Settlements and pending cases are not findings in this classification. “No admitted adjudication” is not a clearance or a complete regulatory-history search.
Publication, method and source
- Issuer CIK
- 0001439222
- Publication as of
- Oct 9, 2026; known by Oct 9, 2026
- Retrieved
- Nov 11, 2026; shared cache no older than five minutes
- RED source refresh state
- fresh within 8d
- Method
- epg.signed_credibility.abstain-unfitted.v1
- Population identity
- sha256:98d4567a9d3793777ced97387b5d300b646dfd15e311888364300df12f95349b
- Graph identity
- c6521b138848011b775d9a6dfb7ac59989b2082fdc729ef4f41456a4e2037f60
- Source
- SEC Forms 3, 4 and 5 for roles; the Midas Edge API's active immutable people-network publication for credibility and admitted findings. GREEN seed evidence can include vendor price histories. No portfolio or account data is sent to this product.
Short-interest history
FINRA reports open short positions for a settlement date. The publication date is later. These are reported positions, with a separate date for each observation.
Compare the reported short exposure around the dates you bought, sold or watched AGIO. A long position benefits from price rises; a short position benefits from falls. A change in these counts does not predict either move.
Settlement Oct 30, 2026
6,524,140 shares short
-370,716 shares (-5.4%) vs Oct 15, 2026
13% of the stored float. Published Nov 10, 2026.
Settlement Oct 15, 2026
6,894,856 shares short
-121,310 shares (-1.7%) vs Sep 30, 2026
13.8% of the stored float. Published Oct 26, 2026.
Settlement Sep 30, 2026
7,016,166 shares short
-541,086 shares (-7.2%) vs Sep 15, 2026
14% of the stored float. Published Oct 9, 2026.
Settlement Sep 15, 2026
7,557,252 shares short
+22,198 shares (+0.3%) vs Aug 31, 2026
Share of float unavailable. Published Sep 24, 2026.
Settlement Aug 31, 2026
7,535,054 shares short
-93,958 shares (-1.2%) vs Aug 14, 2026
Share of float unavailable. Published Sep 10, 2026.
Settlement Aug 14, 2026
7,629,012 shares short
+788,290 shares (+11.5%) vs Jul 31, 2026
Share of float unavailable. Published Aug 25, 2026.
Change = this settlement’s shares short − the previous recorded settlement’s shares short; percentage change divides by that earlier count. A zero earlier count has no percentage change. Split-spanning counts are left uncompared. Float percentages use the stored settlement observation, not today’s float.
Source: stored FINRA equity short-interest records, up to six settlements from the last 240 days. FINRA data and reporting dates · How to read short interest
Dividends and stock splits
See the recorded cash amounts and dates behind AGIO’s income, and the splits that change its share count. Dates below are stored event records, not confirmation of a payment to your account.
Cash-dividend records
No qualified cash-dividend records are stored. This does not establish that the company pays no dividend.
Up to six Polygon cash-dividend events, including recorded ex-dates within the next 120 days. Amounts retain their recorded currency and decimal precision. Historical amounts are not restated to a common split basis, annualized, or converted to dollars.
For a long holding, compare the ex-date with when you held the shares and check the pay date against your broker’s cash history. Owning the stock today does not establish past entitlement. For a short holding, a dividend can create a payment obligation to the share lender.
Ex-dates and special dividend rules · Short-sale dividend obligations · Dividend data definitions
Split history
No qualified split events are stored. This does not establish that the stock has never split.
Up to six stored split dates through Nov 11, 2026. Equivalent vendor ratios are combined; conflicting ratios are left out. This history may be incomplete.
A split changes the share count and per-share price basis; it does not by itself add investment value. Put your holding’s earlier and later share counts on the same basis before comparing them. This applies to both long shares and shares owed on a short position.
How stock splits workPortfolio context
Link an account to see your stake, watchlist and past holdings.
We’ll show you if AGIO is in your portfolio and how much it contributes.
Sign inMarket context
Loading market dates
Smart money context
Holder IQ: MEDIUM
32 smart-money holders: institutions with a high Holder IQ
Q2 2026, filed Sep 23, 2026
Smart-money 13F trend: accumulating (heavy)
Unlock crowding heatmapUnlock filer discoveryInsider context
Sentiment: bearish
Last trade: sell 14 days ago
Read the insider context evidence
What it means for you
Sign in to read your holdings or watchlist context. No personal position or direction is inferred.
What happened
Stored recent-activity label: bearish. This context label is separate from the scored insider signal read.
Why it can matter
A count of reported activity describes a sample, not purchase conviction, an insider’s intent or a future price move. Neutral is not an all-clear, and absent direction is not neutral evidence.
How we got this
The current context rule reads at most 50 nonduplicate issuer/share-class records filed in the last 90 days. It counts a bullish direction or purchase code P toward bullish, and a bearish direction or sale code S toward bearish. A side must exceed the opposite count by more than two to set its label; otherwise nonzero directional counts produce neutral. Calculation unavailable for this saved label: its counts, exact records, as-of time and rule version are not supplied here. Do not substitute the separate scored read’s different window or denominator.
Where the data comes from
Stored SEC Forms 3/4/5 insider-signal records, ordered by filing date with amendment duplicates excluded. Filing date is not transaction date. The last-trade line locates recent reported activity; it does not date or reconstruct the complete count.
Red flags: 0
Read the insider context evidence
What it means for you
Sign in to read your holdings or watchlist context. No personal position or direction is inferred.
What happened
Stored recent-activity label: bearish. This context label is separate from the scored insider signal read.
Why it can matter
A count of reported activity describes a sample, not purchase conviction, an insider’s intent or a future price move. Neutral is not an all-clear, and absent direction is not neutral evidence.
How we got this
The current context rule reads at most 50 nonduplicate issuer/share-class records filed in the last 90 days. It counts a bullish direction or purchase code P toward bullish, and a bearish direction or sale code S toward bearish. A side must exceed the opposite count by more than two to set its label; otherwise nonzero directional counts produce neutral. Calculation unavailable for this saved label: its counts, exact records, as-of time and rule version are not supplied here. Do not substitute the separate scored read’s different window or denominator.
Where the data comes from
Stored SEC Forms 3/4/5 insider-signal records, ordered by filing date with amendment duplicates excluded. Filing date is not transaction date. The last-trade line locates recent reported activity; it does not date or reconstruct the complete count.
Largest 13-F holders · Q2 2026
238 filers reported a long position in AGIO for Q2 2026. 13-F holdings are filed up to 45 days after the quarter ends.
The top 10 hold
52.5%
of the 66M shares 13-F filers reported
Moves vs Q1 2026
8 added2 trimmed
Net shares held
+7.5%
across the 10 holders with a comparable Q1 2026 book
| Rank | Holder | Value | Shares | Shares vs Q1 2026 |
|---|---|---|---|---|
| 1 | BlackRock, Inc. | $239.6M · 6.5M shares | 6.5M | +12.2% |
| 2 | Farallon Capital Management, L.L.C. | $219.6M · 5.9M shares | 5.9M | +4.1% |
| 3 | State Street Corp | $131.1M · 3.5M shares | 3.5M | +5% |
| 4 | Lynx1 Capital Management LP | $126.5M · 3.4M shares | 3.4M | +30.5% |
| 5 | D. E. Shaw & Co., Inc. | $115.3M · 3.1M shares | 3.1M | +15.9% |
| 6 | Vanguard Portfolio Management LLC | $107.6M · 2.9M shares | 2.9M | +11% |
| 7 | Vanguard Capital Management LLC | $99.5M · 2.7M shares | 2.7M | +1.9% |
| 8 | Armistice Capital, LLC | $89.1M · 2.4M shares | 2.4M | -11.6% |
| 9 | Erste Asset Management GmbH | $82M · 2.2M shares | 2.2M | -20.3% |
| 10 | Nomura Asset Management International Inc. | $78.3M · 2.1M shares | 2.1M | +41.2% |
Sign in to see each holder’s Holder IQ, factor-adjusted Holder IQ and rank, and compare these holders with all scored filers. Available on every plan.
Sign in5% holder filings (13D / 13G)
Holders of more than 5% of AGIO file with the SEC within days. A 13D holder may seek to influence the company; a 13G holder is passive. Each holder’s latest filing from the last three years.
| Filed | Holder | % of class |
|---|---|---|
| Aug 3, 2026 | Farallon Capital Management, L.L.C.13G · passive · amended | 9.9% |
| Jul 2, 2026 | Shaw D E & Co L P13G · passive | 5.1% |
| May 15, 2026 | Armistice Capital, LLC13G · passive · amended | 4.57%under 5% |
| May 6, 2026 | Lynx1 Capital Management LP13G · passive | 5.1% |
| Apr 29, 2026 | Vanguard Capital Management LLC13G · passive | 5.27% |
| Mar 26, 2026 | Vanguard Group Inc13G · passive · amended | 0%under 5% |
Moves the factor model did not explain
How much of AGIO’s move accompanied the market and its measured style leanings, and how much was left? The residual is unexplained by this fitted model. It does not establish a cause, skill or future alpha.
- Market
- -2.46%
- Style leanings
- +2.98%
- Unexplained residual
- +4.62%
- Stock move
- +5.13%
Window contributions are percentage points of starting stock value. The market bar is the fitted common intercept, not an index return. Market + styles + residual = stock move; opposite signs can offset. Source: daily_returns, dated security_factor_exposures × barra_factor_returns, and stored security_specific_returns; 2026-10-13–2026-11-10, model v1.2.0. Returns are dimensionless on the USD listing; no currency conversion.
Link an account with dated transactions to see what share of your own holding’s move since its purchase-date close was unexplained, with long and short positions distinguished. Your private holdings never enter this public chart.
Dated model observations (20)
Daily percentage returns, not window contributions. Source: the same dated warehouse rows and model v1.2.0; observed 2026-11-11T20:45:49.400Z. Absent sessions are never interpolated; missing or failed inputs stay unavailable.
| Date | Stock | Market | Styles | Residual |
|---|---|---|---|---|
| +2.52% | -1.18% | -2.14% | +5.84% | |
| +4.36% | +0.52% | +2.01% | +1.83% | |
| -3.09% | -1.05% | -2.61% | +0.57% | |
| +11.43% | +0.36% | +0.78% | +10.29% | |
| +4.99% | +0.43% | +1.30% | +3.25% | |
| +1.47% | +0.49% | +0.07% | +0.92% | |
| +0.03% | -1.09% | +0.43% | +0.69% | |
| -0.51% | -0.46% | +0.56% | -0.61% | |
| -0.41% | +0.50% | -1.74% | +0.83% | |
| +3.20% | +0.68% | +0.06% | +2.46% | |
| +0.24% | +0.37% | -0.20% | +0.07% | |
| -2.33% | -0.46% | +0.69% | -2.56% | |
| -17.94% | -1.77% | -1.29% | -14.88% | |
| -1.96% | -0.24% | +0.23% | -1.96% | |
| +4.17% | +0.35% | +2.00% | +1.83% | |
| +0.58% | +1.75% | +2.34% | -3.51% | |
| -9.91% | -3.95% | -4.29% | -1.67% | |
| +4.03% | +0.71% | +4.43% | -1.11% | |
| +6.70% | +2.50% | +2.20% | +2.00% | |
| +1.21% | -0.29% | -1.14% | +2.64% |
How this split is calculated
Each day uses that day’s fitted market intercept and style exposures multiplied by that day’s published factor returns. Their sum plus the independently stored residual must reconcile to the stock return. Window effects are weighted by stock wealth at each day’s start and added; the stock return compounds. Every expected US market session must be present and pass source, identity, model and numerical checks. This retrospective fit is an explanation of measured returns, not evidence of causation or an investable forecast. The window ends at the latest published model session, which can lag the market; today’s unfinished session is excluded.
What insiders reported owning
Reading dated filing evidence…
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