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Crinetics Pharmaceuticals, Inc.

For the period ended Jun 30, 2026. Filed Aug 3, 2026.

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About this filing

A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.

Jun 30, 2026 · Filed Aug 3, 2026

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Item 6. Exhibits

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EXHIBIT INDEX

ExhibitNumber · Incorporated by Reference · FiledHerewith
Exhibit Description · Form · File No. · Exhibit · Filing Date
2.1†Agreement and Plan of Merger by and among Crinetics Pharmaceuticals, Inc., Vertex Pharmaceuticals Incorporated and Clark Merger Sub, Inc., dated July 6, 2026.8-K001-385832.1*7/6/2026
3.1Amended and Restated Certificate of Incorporation8-K001-385833.37/20/2018
3.2Amended and Restated Bylaws8-K001-385833.112/12/2023
4.1Specimen Stock Certificate Evidencing the Shares of Common StockS-1/A333-2258244.17/9/2018
10.1Independent Consultant Agreement, effective as of April 10, 2026, between Crinetics Pharmaceuticals, Inc. and Jeff Knight.8-K10.14/10/2026
31.1Certification of Chief Executive Officer pursuant to Rules 13(a)-14(a) and 15d-14(a), as adopted pursuant to Section 302 of the Sarbanes Oxley Act of 2002X
31.2Certification of Chief Financial Officer pursuant to Rules 13(a)-14(a) and 15d-14(a), as adopted pursuant to Section 302 of the Sarbanes Oxley Act of 2002X
32.1*Certification of Chief Executive Officer and Chief Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes Oxley Act of 2002X
101.INSInline XBRL Instance Document – the instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the inline XBRL documentX
101.SCHInline XBRL Taxonomy Extension Schema Document.X
104Cover Page Interactive Data File (formatted as inline XBRL and contained in Exhibit 101)X

†Schedules and similar attachments have been omitted pursuant to Item 601(a)(5) of Regulation S-K. A copy of any omitted schedule will be furnished supplementally to the SEC upon request.

*The certification attached as Exhibit 32.1 that accompanies this Report is not deemed filed with the SEC and is not to be incorporated by reference into any filing of Crinetics under the U.S. Securities Act of 1933, as amended, or the Exchange Act, whether made before or after the date of this Report, irrespective of any general incorporation language contained in such filing.

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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.