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Annexon, Inc.

For the period ended Dec 31, 2025. Filed Mar 30, 2026.

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About this filing

A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Mar 30, 2026

ANNX$4.21-0.5%Stored close · as of Nov 10, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Contents

Item 15. Exhibits, Financial Statement Schedules

(a) The following documents are filed as part of this report:

  1. Financial Statements

Information in response to this Item is included in Part II, Item 8 of this Annual Report on Form 10-K.

  1. Financial Statement Schedules

All schedules are omitted because they are not applicable or the required information is shown in the financial statements or notes thereto.

  1. Exhibits

Exhibit Index

ExhibitNo · Description of Exhibit · Incorporated by Reference
Form · File No. · Exhibit · Filing Date · FiledHerewith
3.1Amended and Restated Certificate of Incorporation.8-K001-394023.107/28/20
3.2Amended and Restated Bylaws.8-K001-394023.207/28/20
4.1Reference is made to Exhibits 3.1 through 3.2.
4.2Form of Common Stock Certificate.S-1333-2396474.207/02/20
4.3Description of Registrant’s Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934.X
4.4Form of Pre-Funded Warrant (2022).8-K001-394024.107/08/22
4.5Form of Common Warrant.8-K001-394024.207/08/22
4.6Form of Pre-Funded Warrant (2023).8-K/A001-394024.112/22/23
4.7Form of Pre-Funded Warrant (2024).8-K001-394024.106/07/24
4.8Form of Common Warrant Amendment8-K001-394024.106/25/2025
4.9Form of Pre-Funded Warrant (2025)8-K001-394024.111/14/2025
10.1†Exclusive (Equity) Agreement, dated November 21, 2011, by and between the Registrant and The Board of Trustees of the Leland Stanford Junior University.S-1333-23964710.207/02/20
10.2Lease, dated December 18, 2020, by and between the Registrant and HCP LS Brisbane, LLC.8-K001-3940210.112/22/20
10.3(a)+2011 Incentive Award Plan.S-1/A333-23964710.4(a)07/20/20
10.3(b)+Form of Stock Option Agreement under 2011 Equity Incentive Plan.S-1333-23964710.4(b)07/02/20
ExhibitNo · Description of Exhibit · Incorporated by Reference
Form · File No. · Exhibit · Filing Date · FiledHerewith
10.4(a)+2020 Incentive Award Plan.S-8333-24010199.2(a)07/24/20
10.4(b)+Form of Stock Option Grant Notice and Stock Option Agreement under the 2020 Incentive Award Plan.S-1333-23964710.5(b)07/02/20
10.4(c)+Form of Restricted Stock Award Grant Notice and Restricted Stock Award Agreement under the 2020 Incentive Award Plan.S-1333-23964710.5(c)07/02/20
10.4(d)+Form of Restricted Stock Unit Award Grant Notice and Restricted Stock Unit Award Agreement under the 2020 Incentive Award Plan.S-1333-23964710.5(d)07/02/20
10.5+Employee Stock Purchase Plan.S-8333-24010199.307/24/20
10.6+Employment Agreement by and between the Registrant and Douglas Love, Esq.S-1333-23964710.707/02/20
10.7+Employment Agreement by and between the Registrant and Jennifer Lew.S-1333-23964710.907/02/20
10.8+Employment Agreement by and between the Registrant and Michael Overdorf.S-1/A333-23964710.1107/20/20
10.9+Non-Employee Director Compensation Program.10-Q001-3940210.108/14/25
10.10+Form of Indemnification and Advancement Agreement for directors and officers.S-1333-23964710.1207/02/20
10.11+Employment Agreement by and between the Registrant and Dean Richard Artis, Ph.D.10-K001-3940210.1203/06/22
10.12+Annexon, Inc. 2022 Employment Inducement Award Plan.10-Q001-3940210.2(a)08/08/22
10.13+Form of Stock Option Grant Notice and Stock Option Agreement under the 2022 Employment Inducement Award Plan.10-Q001-3940210.2(b)08/08/22
10.14+Form of Restricted Stock Unit Award Grant Notice and Restricted Stock Unit Award Agreement under the 2022 Employment Inducement Award Plan.10-Q001-3940210.2(c)08/08/22
10.15+Employment Agreement by and between the Registrant and Jamie Dananberg, M.D.10-Q001-3940210.2#08/07/23
10.16#Sales Agreement, dated as of March 30, 2026, by and between Annexon Inc. and TD Securities (USA) LLC.X
19.1Insider Trading Compliance Policy10-K001-3940219.103/03/25
21.1List of subsidiaries.S-1333-23964721.107/02/20
ExhibitNo · Description of Exhibit · Incorporated by Reference
Form · File No. · Exhibit · Filing Date · FiledHerewith
23.1 · Consent of Independent Registered Public Accounting Firm. · X
24.1 · Power of Attorney (included in the signature page hereto). · X
31.1 · Certification of Principal Executive Officer Pursuant to Rules 13a-14(a) and 15d-14(a) under the Securities Exchange Act of 1934, as amended. · X
31.2 · Certification of Principal Financial Officer Pursuant to Rules 13a-14(a) and 15d-14(a) under the Securities Exchange Act of 1934, as amended. · X
32.1* · Certification of Chief Executive Officer and Chief Financial Officer Pursuant to 18 U.S.C. Section 1350, As Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, as amended. · X
97.1Policy for Recovery of Erroneously Awarded Compensation.10-K001-3940297.103/26/24
101.INSInline XBRL Instance DocumentX
101.SCHInline XBRL Taxonomy Extension Schema With Embedded Linkbase DocumentsX
104Cover Page Interactive Data File (formatted as inline XBRL and contained in Exhibit 101)X
  • Indicates management contract or compensatory plan.

† Certain portions of this document that constitute confidential information have been redacted in accordance with Regulation S-K, Item 601(b)(10).

Certain schedules and exhibits have been omitted pursuant to Item 601(a)(5) of Regulation S-K. A copy of any omitted schedule and/or exhibit will be furnished to the SEC upon request.

  • The certification attached as Exhibit 32.1 that accompanies this Annual Report on Form 10-K pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, is not deemed “filed” by the Registrant for purposes of Section 18 of the Securities Exchange Act of 1934, as amended.
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