Amylyx Pharmaceuticals Inc

Item 1. Legal Proceedings.

On February 9, 2024, a putative class action lawsuit was filed in the U.S. District Court for the Southern District of New York against the Company and certain of our current and former officers (Shih v. Amylyx Pharmaceuticals, Inc., et al., Case Number 1:24-CV-00988, or the Shih Complaint). Plaintiff filed an amended complaint on June 24, 2024. The Shih Complaint asserts a claim against all defendants for alleged violations of Section 10(b) of the Exchange Act and Rule 10b-5 promulgated thereunder and a claim under Section 20(a) against certain current and former officers as alleged controlling persons. The Shih Complaint alleges that defendants made materially false and misleading statements related to the commercial results and prospects for RELYVRIO. The Shih Complaint seeks unspecified damages, interest, costs and attorneys’ fees, and other unspecified relief that the court deems appropriate. The Company intends to defend against the Shih Complaint vigorously, and filed a motion to transfer venue on July 11, 2024. On July 12, 2024, the court granted the motion to transfer, ordering the clerk to transfer the case to the United States District Court for the District of Massachusetts, or the Order. The parties await a new docket number and assigned judge in light of the Order regarding the transfer to the District of Massachusetts. At this time, an estimate of the impact, if any, of the claims made in the Shih Complaint cannot be made.