AMGEN INC
For the period ended Dec 31, 2024. Filed Feb 14, 2025.
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FY2024 · Filed Feb 14, 2025
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DEFINED TERMS AND PRODUCTSii
Defined Terms and Products
Defined terms
We use several terms in this Form 10-K, including but not limited to those that are finance, regulation and disease-state related as well as names of other companies, which are given below.
| Term | Description |
|---|---|
| 2017 Tax Act | Tax Cuts and Jobs Act of 2017 |
| 340B Program | Federal 340B Drug Pricing Program |
| Amended 2009 Plan | Amended and Restated 2009 Equity Incentive Plan |
| AOCI | accumulated other comprehensive income (loss) |
| ASR | Accelerated Share Repurchase |
| AstraZeneca | AstraZeneca plc |
| ASU | Accounting Standards Update |
| ATMOS | Amgen Technology and Medical Organizations |
| B-ALL | B-cell precursor acute lymphoblastic leukemia |
| BeiGene | BeiGene, Ltd. |
| BiTE® | bispecific T-cell engager |
| BLA | Biologics License Application |
| BPCIA | Biologics Price Competition and Innovation Act of 2009 |
| CCPA | California Consumer Privacy Act of 2018 |
| CDT | Cybersecurity & Digital Trust |
| CGRP | calcitonin gene-related peptide |
| ChemoCentryx | ChemoCentryx, Inc. |
| chemotherapy | anticancer medicines |
| CHMP | Committee for Medicinal Products for Human Use |
| CIO | Chief Information Officer |
| CISO | Chief Information Security Officer |
| CMS | Centers for Medicare & Medicaid Services |
| COSO | Committee of Sponsoring Organizations of the Treadway Commission |
| CRCC | Corporate Responsibility and Compliance Committee |
| DLL3 | delta-like ligand 3 |
| DOJ | U.S. Department of Justice |
| EC | European Commission |
| Eczacıbaşı | EIS Eczacıbaşı İlaç, Sınai ve Finansal Yatırımlar Sanayi ve Ticaret A.Ş. |
| EMA | European Medicines Agency |
| EPO | European Patent Office |
| EPS | earnings per share |
| ESG | environmental, social and governance |
| EU | European Union |
| FASB | Financial Accounting Standards Board |
| FCPA | U.S. Foreign Corrupt Practices Act |
| FDA | U.S. Food and Drug Administration |
| FDCA | Federal Food, Drug, and Cosmetic Act |
| Fitch | Fitch Ratings, Inc. |
| FTC | Federal Trade Commission |
| GAAP | U.S. generally accepted accounting principles |
| GDPR | General Data Protection Regulation |
| Gensenta | Gensenta İlaç Sanayi ve Ticaret A.Ş. |
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| Term | Description |
|---|---|
| HHS | U.S. Department of Health & Human Services |
| Horizon | Horizon Therapeutics plc |
| IGF-1R | insulin-like growth factor-1 receptor |
| IND | Investigational New Drug Application |
| IPR&D | in-process research and development |
| IRA | Inflation Reduction Act of 2022 |
| IRS | Internal Revenue Service |
| KRAS | Kirsten rat sarcoma viral oncogene |
| Kyowa Kirin | Kyowa Kirin Co., Ltd. |
| LDL-C | low-density lipoprotein cholesterol |
| Lilly | Eli Lilly and Company |
| MAA | Marketing Authorisation Application |
| MD&A | management’s discussion and analysis |
| Moody’s | Moody’s Investors Service, Inc. |
| MRD | minimal residual disease |
| Neumora | Neumora Therapeutics, Inc. |
| NOL | net operating loss |
| NSCLC | non-small cell lung cancer |
| OECD | Organisation for Economic Co-operation and Development |
| OIG | Office of Inspector General |
| PBM | pharmacy benefit manager |
| PCSK9 | proprotein convertase subtilisin/kexin type 9 |
| PDAB | Prescription Drug Affordability Board |
| PDE4 | phosphodiesterase 4 |
| R&D | research and development |
| RANKL | receptor activator of nuclear factor kappa-B ligand |
| RAR | Revenue Agent Report |
| RAS | Rat sarcoma viral oncogene |
| Regeneron | Regeneron Pharmaceuticals, Inc. |
| REMS | Risk Evaluation and Mitigation Strategy |
| ROU | right-of-use |
| ROW | rest of world |
| RSUs | restricted stock units |
| S&P | Standard & Poor’s Financial Services LLC |
| SEC | U.S. Securities and Exchange Commission |
| SG&A | selling, general and administrative |
| SOFR | Secured Overnight Financing Rate |
| TED | thyroid eye disease |
| Teneobio | Teneobio, Inc. |
| U.S. Treasury | U.S. Department of Treasury |
| USPTO | U.S. Patent and Trademark Office |
| UTB | unrecognized tax benefit |
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Products
The brand names of our products, our delivery devices and certain of our product candidates and their associated generic names are given below.
| Term | Description |
|---|---|
| ACTIMMUNE | ACTIMMUNE® (interferon gamma-1b) |
| Aimovig | Aimovig® (erenumab-aooe) |
| AMJEVITA/AMGEVITA | AMJEVITA® (adalimumab-atto)/AMGEVITA™ (adalimumab) |
| Aranesp | Aranesp® (darbepoetin alfa) |
| AutoTouch | AutoTouch® |
| AVSOLA | AVSOLA® (infliximab-axxq) |
| BKEMV/BEKEMV | BKEMV™ (eculizumab-aeeb)/BEKEMV™ (eculizumab) |
| BLINCYTO | BLINCYTO® (blinatumomab) |
| BUPHENYL | BUPHENYL® (sodium phenylbutyrate) |
| ConfiPen | ConfiPen™ |
| Corlanor | Corlanor® (ivabradine) |
| DUEXIS | DUEXIS® (ibuprofen and famotidine) |
| ENBREL | Enbrel® (etanercept) |
| ENBREL Mini | ENBREL Mini® |
| EPOGEN | EPOGEN® (epoetin alfa) |
| EVENITY | EVENITY® (romosozumab-aqqg) |
| IMDELLTRA/IMDYLLTRA | IMDELLTRA® (tarlatamab-dlle)/IMDYLLTRA® (tarlatamab) |
| IMLYGIC | IMLYGIC® (talimogene laherparepvec) |
| KANJINTI | KANJINTI® (trastuzumab-anns) |
| KRYSTEXXA | KRYSTEXXA® (pegloticase) |
| KYPROLIS | KYPROLIS® (carfilzomib) |
| LUMAKRAS/LUMYKRAS | LUMAKRAS®/LUMYKRAS™ (sotorasib) |
| MariTide | Maridebart cafraglutide (formerly AMG 133) |
| MVASI | MVASI® (bevacizumab-awwb) |
| Neulasta | Neulasta® (pegfilgrastim) |
| NEUPOGEN | NEUPOGEN® (filgrastim) |
| Nplate | Nplate® (romiplostim) |
| Onpro | Onpro® |
| Otezla | Otezla® (apremilast) |
| Parsabiv | Parsabiv® (etelcalcetide) |
| PAVBLU | PAVBLU™ (aflibercept-ayyh, formerly ABP 938) |
| PENNSAID | PENNSAID® (diclofenac sodium topical solution) 2% |
| PROCYSBI | PROCYSBI® (cysteamine bitartrate) |
| Prolia | Prolia® (denosumab) |
| Pushtronex | Pushtronex® |
| QUINSAIR | QUINSAIR® (levofloxacin) |
| RAVICTI | RAVICTI® (glycerol phenylbutyrate) |
| RAYOS | RAYOS® (prednisone) |
| Repatha | Repatha® (evolocumab) |
| RIABNI | RIABNI® (rituximab-arrx) |
| Sensipar/Mimpara | Sensipar®/Mimpara™ (cinacalcet) |
| SureClick | SureClick® |
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| Term | Description |
|---|---|
| TAVNEOS | TAVNEOS® (avacopan) |
| TEPEZZA | TEPEZZA® (teprotumumab-trbw) |
| TEZSPIRE | TEZSPIRE® (tezepelumab-ekko) |
| UPLIZNA | UPLIZNA® (inebilizumab-cdon) |
| Vectibix | Vectibix® (panitumumab) |
| WEZLANA/WEZENLA | WEZLANA™ (ustekinumab-auub) / WEZENLA™ (ustekinumab) |
| XGEVA | XGEVA® (denosumab) |
Products referenced in this report that are not included in the above list are trademarks of their respective owners. They are Avastin®, BESPONSA®, Cosentyx®, DARZALEX®, DUPIXENT®, ERBITUX®, EYLEA®, FASENRA®, Herceptin®, HUMIRA®, HYRIMOZ®, KEYTRUDA®, LEQVIO®, Nucala®, POMALYST®/IMNOVID®, PRALUENT®, PROCRIT®, PROMACTA®/REVOLADE™, Remicade®, REVLIMID®, RINVOQ®, Rituxan®/MabThera®, Skyrizi®, SOLIRIS®, SOTYKTU®, STELARA®, Taltz®, Teribone™, Tremfya®, VELCADE®, Xeljanz®and XOLAIR®.
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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.